mog 35–55 peptide genemed synthesis Search Results


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Genemed Synthesis myelin oligodendrocyte glycoprotein mog peptide mog 35 55
Myelin Oligodendrocyte Glycoprotein Mog Peptide Mog 35 55, supplied by Genemed Synthesis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 86 stars, based on 1 article reviews
myelin oligodendrocyte glycoprotein mog peptide mog 35 55 - by Bioz Stars, 2026-10
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Genemed Biotechnologies mog 35 55 peptide
Ninjurin-1 + myeloid cells enhance CD4 + T cell activation and cytokine production. CD45 + B220 - CD3 - CD11b + Ly6G - Ninjurin-1+ or Ninjurin-1 - myeloid cells were flow-sorted and co-cultured with CFSE-labeled CD4 + T cells isolated from 2D2 mice. Cells were stimulated with <t>MOG</t> <t>35–55</t> peptide in 96-well plates for 72 hours. (A) T cell proliferation, measured by CFSE dilution, was greater when CD4 + T cells were co-cultured with Ninjurin-1 + myeloid cells compared to Ninjurin-1 - cells. Controls included CD4 + T cells cultured without antigen-presenting cells (APCs) or without MOG 35–55 peptide. (B) CD4 + T cells co-cultured with Ninjurin-1 + myeloid cells showed increased expression of CD25 and TNF-α, indicating higher levels of activation and inflammatory cytokine production. Data represent n = 4 independent experiments and are shown as mean ± SEM. Statistical analysis was performed using two-way ANOVA (*p < 0.05, **p < 0.01, ***p < 0.001).
Mog 35 55 Peptide, supplied by Genemed Biotechnologies, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mog+35%E2%80%9355+peptide+genemed+synthesis/35+55+mog+peptide/pmc13124630-109-23-26
Average 86 stars, based on 1 article reviews
mog 35 55 peptide - by Bioz Stars, 2026-10
86/100 stars
  Buy from Supplier

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Ninjurin-1 + myeloid cells enhance CD4 + T cell activation and cytokine production. CD45 + B220 - CD3 - CD11b + Ly6G - Ninjurin-1+ or Ninjurin-1 - myeloid cells were flow-sorted and co-cultured with CFSE-labeled CD4 + T cells isolated from 2D2 mice. Cells were stimulated with MOG 35–55 peptide in 96-well plates for 72 hours. (A) T cell proliferation, measured by CFSE dilution, was greater when CD4 + T cells were co-cultured with Ninjurin-1 + myeloid cells compared to Ninjurin-1 - cells. Controls included CD4 + T cells cultured without antigen-presenting cells (APCs) or without MOG 35–55 peptide. (B) CD4 + T cells co-cultured with Ninjurin-1 + myeloid cells showed increased expression of CD25 and TNF-α, indicating higher levels of activation and inflammatory cytokine production. Data represent n = 4 independent experiments and are shown as mean ± SEM. Statistical analysis was performed using two-way ANOVA (*p < 0.05, **p < 0.01, ***p < 0.001).

Journal: Frontiers in Immunology

Article Title: Dual role of Ninjurin-1 in myeloid cell adhesion and inflammation in relapse-remitting EAE

doi: 10.3389/fimmu.2026.1803382

Figure Lengend Snippet: Ninjurin-1 + myeloid cells enhance CD4 + T cell activation and cytokine production. CD45 + B220 - CD3 - CD11b + Ly6G - Ninjurin-1+ or Ninjurin-1 - myeloid cells were flow-sorted and co-cultured with CFSE-labeled CD4 + T cells isolated from 2D2 mice. Cells were stimulated with MOG 35–55 peptide in 96-well plates for 72 hours. (A) T cell proliferation, measured by CFSE dilution, was greater when CD4 + T cells were co-cultured with Ninjurin-1 + myeloid cells compared to Ninjurin-1 - cells. Controls included CD4 + T cells cultured without antigen-presenting cells (APCs) or without MOG 35–55 peptide. (B) CD4 + T cells co-cultured with Ninjurin-1 + myeloid cells showed increased expression of CD25 and TNF-α, indicating higher levels of activation and inflammatory cytokine production. Data represent n = 4 independent experiments and are shown as mean ± SEM. Statistical analysis was performed using two-way ANOVA (*p < 0.05, **p < 0.01, ***p < 0.001).

Article Snippet: CFSE + CD4 + T cells (100,000/well) were then co-cultured with either Ninjurin-1 - or Ninjurin-1 + sorted cells (40,000/well) with 20 μg/ml MOG 35–55 peptide (Genemed Biotechnologies Inc.) into a 96 well plate for 72 hours.

Techniques: Activation Assay, Cell Culture, Labeling, Isolation, Expressing