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Genemed Synthesis
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Genemed Biotechnologies
mog 35 55 peptide ![]() Mog 35 55 Peptide, supplied by Genemed Biotechnologies, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/mog+35%E2%80%9355+peptide+genemed+synthesis/35+55+mog+peptide/pmc13124630-109-23-26 Average 86 stars, based on 1 article reviews
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Image Search Results
Journal: Frontiers in Immunology
Article Title: Dual role of Ninjurin-1 in myeloid cell adhesion and inflammation in relapse-remitting EAE
doi: 10.3389/fimmu.2026.1803382
Figure Lengend Snippet: Ninjurin-1 + myeloid cells enhance CD4 + T cell activation and cytokine production. CD45 + B220 - CD3 - CD11b + Ly6G - Ninjurin-1+ or Ninjurin-1 - myeloid cells were flow-sorted and co-cultured with CFSE-labeled CD4 + T cells isolated from 2D2 mice. Cells were stimulated with MOG 35–55 peptide in 96-well plates for 72 hours. (A) T cell proliferation, measured by CFSE dilution, was greater when CD4 + T cells were co-cultured with Ninjurin-1 + myeloid cells compared to Ninjurin-1 - cells. Controls included CD4 + T cells cultured without antigen-presenting cells (APCs) or without MOG 35–55 peptide. (B) CD4 + T cells co-cultured with Ninjurin-1 + myeloid cells showed increased expression of CD25 and TNF-α, indicating higher levels of activation and inflammatory cytokine production. Data represent n = 4 independent experiments and are shown as mean ± SEM. Statistical analysis was performed using two-way ANOVA (*p < 0.05, **p < 0.01, ***p < 0.001).
Article Snippet: CFSE + CD4 + T cells (100,000/well) were then co-cultured with either Ninjurin-1 - or Ninjurin-1 + sorted cells (40,000/well) with 20 μg/ml
Techniques: Activation Assay, Cell Culture, Labeling, Isolation, Expressing